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KKLALALAKKWLPLAKKLALALAKK details |
| Primary information | |
|---|---|
| ID | antitb_1414, |
| Name | 25154927 |
| N-Terminal modification | D-LAk120-AP13 |
| C-Terminal Modification | KKLALALAKKWLPLAKKLALALAKK |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 25 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis XDR strain |
| Inhibition Concentration | in vitro |
| Sequence | 2014 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | NA |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1420, |
| Name | 25154927 |
| N-Terminal modification | D-LAk120-AP13 |
| C-Terminal Modification | KKLALALAKKWLPLAKKLALALAKK |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 25 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis XDR strain |
| Inhibition Concentration | in vitro |
| Sequence | 2014 |
| Cytotoxicity | THP-1 cell line |
| In vivo Model | EC50 = 32.1 ± 4.8 μM |
| Lethal Dose | Cytotoxic at > 25 μM |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | NA |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1426, |
| Name | 25154927 |
| N-Terminal modification | D-LAk120-AP13 |
| C-Terminal Modification | KKLALALAKKWLPLAKKLALALAKK |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 25 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis MDR strain GB2 |
| Inhibition Concentration | Ex vivo |
| Sequence | 2014 |
| Cytotoxicity | THP-1 cell line |
| In vivo Model | NA |
| Lethal Dose | Cytotoxic above 3.13 μM |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | NA |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1430, |
| Name | 25154927 |
| N-Terminal modification | D-LAk120-AP13 |
| C-Terminal Modification | KKLALALAKKWLPLAKKLALALAKK |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 25 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis XDR strain WYC-11 |
| Inhibition Concentration | Ex vivo |
| Sequence | 2014 |
| Cytotoxicity | THP-1 cell line |
| In vivo Model | NA |
| Lethal Dose | Cytotoxic above 3.13 μM |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | NA |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1431, |
| Name | 25154927 |
| N-Terminal modification | D-LAk120-AP13 |
| C-Terminal Modification | KKLALALAKKWLPLAKKLALALAKK |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 25 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis XDR strain WYC-11 |
| Cell Line | MIC = 3.13 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | THP-1 cell line |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | NA |
| PMID | INH+D-LAK120-HP13 |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |